SCHEMBL21235702

SCHEMBL21235702

OCC(CO)(CO)COCc1ccc2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.44
CYP1A2 P05177 2/20 0.43
CYP2A6 P11509 1/20 0.43
GBA1 P04062 2/20 0.43
UGCG Q16739 2/20 0.43
GBA2 Q9HCG7 2/20 0.43
RAB9A P51151 1/20 0.42
SLC1A3 P43003 1/20 0.41
SLC1A2 P43004 1/20 0.41
SLC1A1 P43005 1/20 0.41
SLC6A2 P23975 3/20 0.41
SLC6A4 P31645 3/20 0.41
SLC6A3 Q01959 3/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
HTR7 P34969 1/20 0.41
HTR2B P41595 1/20 0.41
HTR3A P46098 1/20 0.41
HTR4 Q13639 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL433146 0.80 CYP1A2 (0.58) KDM4ECYP1A2CYP2A6RAB9ASLC1A3
SCHEMBL13301374 0.79 CYP1A2 (0.50) CYP1A2CYP2A6RAB9ASLC1A3SLC1A2
SCHEMBL5375962 0.78 KDM4E (0.67) KDM4EPOLBCYP1A2SLC6A2SLC6A3
SCHEMBL4223879 0.77 GBA1 (0.48) KDM4ECYP1A2CYP2A6GBA1UGCG
SCHEMBL29705157 0.75 KDM4E (0.62) KDM4EPOLBCYP1A2SLC6A2SLC6A3
SCHEMBL12308438 0.75 KDM4E (0.49) KDM4ECYP1A2CYP2A6GBA1UGCG
SCHEMBL25753060 0.75 KDM4E (0.49) KDM4ECYP1A2CYP2A6GBA1UGCG
SCHEMBL25753059 0.75 KDM4E (0.49) KDM4ECYP1A2CYP2A6GBA1UGCG
SCHEMBL7648436 0.74 TSHR (0.62) CYP1A2CYP2A6RAB9ASLC1A3SLC1A2
SCHEMBL16174483 0.74 CYP1A2 (0.52) KDM4ECYP1A2CYP2A6RAB9ASLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019151384-A1 RADIOACTIVE PHARMACEUTICAL 国立大学法人千葉大学 2019-08-08 WO disclosed