Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648436 | 0.94 | TSHR (0.62) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| Oxirane SCHEMBL11769488 | 0.90 | ALOX5 (0.49) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL16174483 | 0.89 | CYP1A2 (0.52) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL13977956 | 0.87 | CYP1A2 (0.50) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL19249099 | 0.87 | CYP1A2 (0.50) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL19508917 | 0.87 | CYP1A2 (0.50) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL2108042 | 0.87 | CYP1A2 (0.50) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL19249290 | 0.87 | CYP1A2 (0.50) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL19249093 | 0.87 | CYP1A2 (0.50) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL28367677 | 0.87 | RAB9A (0.51) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 858 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12441741-B2 | Ring closing synthesis of macrocyclic MCL-1 inhibitor intermediates | AMGEN INC. (US) | 2025-10-14 | — | — | US | claimed |
| EP-4577644-A1 | BIOCATALYSTS AND METHODS THEREOF | Tesaro, Inc. (US) | 2025-07-02 | — | — | EP | claimed |
| EP-4146636-B1 | SYNTHESIS OF VINYLIC PROTECTED ALCOHOL INTERMEDIATES | AMGEN INC (US) | 2025-06-11 | — | — | EP | claimed |
| CN-119698468-A | Biocatalysts and methods thereof | 特沙诺有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-119585901-A | Pre-lithiated electrode material, method for producing same, secondary battery, and power utilization device | 宁德时代新能源科技股份有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-110981873-B | Preparation method for synthesizing pyrroloquinoline quinone by five-step method | 江西农业大学 | 2025-01-24 | — | — | CN | claimed |
| CN-119156438-A | Perfume composition for sleep improvement | 国际香料和香精公司 | 2024-12-17 | — | — | CN | claimed |
| CN-118908912-A | Synthesis of vinyl protected alcohol intermediates | 安进公司 | 2024-11-08 | — | — | CN | claimed |
| CN-118271233-A | Nilaparil manufacturing method | 特沙诺有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-115485268-B | Synthesis of vinyl protected alcohol intermediates | 安进公司 | 2024-06-18 | — | — | CN | claimed |
| WO-2017211820-A1 | METHODS FOR THE PREPARATION OF DEOXYCHOLIC ACID, AND INTERMEDIATES USEFUL IN THE PREPARATION OF DEOXYCHOLIC ACID | BIONICE, S.L.U. (ES) | 2017-12-14 | — | — | WO | claimed |
| WO-2017018835-A1 | METHOD OF PREPARING TDM-621 | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2017-02-02 | — | — | WO | claimed |
| EP-2635547-A1 | CHIRAL INTERMEDIATES USEFUL FOR THE PREPARATION OF HYDROXYPHOSPHINE LIGANDS | United Phosphorus Limited (IN) | 2013-09-11 | — | — | EP | claimed |
| US-20130217900-A1 | CHIRAL INTERMEDIATES USEFUL FOR THE PREPARATION OF HYDROXYPHOSPHINE LIGANDS | UNITED PHOSPHORUS LIMITED (IN) | 2013-08-22 | — | — | US | claimed |
| WO-2012131077-A1 | SOMATOSTATIN MIMETICS | NATIONAL UNIVERSITY OF IRELAND, GALWAY (IE) | 2012-10-04 | — | — | WO | claimed |
| WO-2012059807-A1 | CHIRAL INTERMEDIATES USEFUL FOR THE PREPARATION OF HYDROXYPHOSPHINE LIGANDS | UNITED PHOSPHORUS LIMITED (IN) | 2012-05-10 | — | — | WO | claimed |
| EP-1113105-B1 | Human sweat malodor counteractant composition and process for using same | INT FLAVORS & FRAGRANCES INC (US) | 2006-04-05 | — | — | EP | claimed |
| EP-0557419-B1 | GRANULAR DETERGENT OR BLEACHING COMPOSITIONS CONTAINING AMIDOPEROXYACID BLEACH AND PERFUME | PROCTER & GAMBLE (US) | 1996-01-17 | — | — | EP | claimed |
| EP-0404470-B1 | Fragrance compositions and their use in detergent products | QUEST INT (NL) | 1994-04-13 | — | — | EP | claimed |
| EP-0005618-B1 | DEODORANT PRODUCTS, PREPARATION AND USE THEREOF | UNILEVER PLC (GB) | 1982-06-09 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217900-A1 | CHIRAL INTERMEDIATES USEFUL FOR THE PREPARATION OF HYDROXYPHOSPHINE LIGANDS | CYP21A2, HRH3, P4HA1 | CYP1A2 323/4885CYP2A6 693/4885RAB9A 4006/4885 |
| US-12441741-B2 | Ring closing synthesis of macrocyclic MCL-1 inhibitor intermediates | MCL1, BAK1, BCLAF1 | CYP1A2 2669/4885CYP2A6 3362/4885RAB9A 3878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.