Phosphoric Acid

Phosphoric Acid

SCHEMBL2123612

O=P(O)(O)O.O=P([O-])(O)O.O=P([O-])(O)O.[K+].[K+]

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ SLC34A1 Q06495 1/20 0.90
▸ LMNA P02545 2/20 0.40
▸ KDM4E B2RXH2 2/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ MMP2 P08253 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ FDPS P14324 1/20 0.33
▸ BLM P54132 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ CA1 P00915 2/20 0.30
▸ CA4 P22748 2/20 0.30
▸ CA5A P35218 2/20 0.30
▸ CA5B Q9Y2D0 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL15393192 1.00 SLC34A1 (0.90) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL2806090 1.00 SLC34A1 (0.90) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL17459504 1.00 SLC34A1 (0.90) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL4003820 1.00 SLC34A1 (0.90) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL1851174 1.00 SLC34A1 (0.90) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL6408390 1.00 SLC34A1 (0.90) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL5955535 1.00 SLC34A1 (0.90) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL14119492 1.00 SLC34A1 (0.90) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL17042378 1.00 SLC34A1 (0.90) SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL5955338 1.00 SLC34A1 (0.90) SLC34A1LMNAKDM4ECYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112522225-A Method for modifying uricase by polyethylene glycol 鲁南制药集团股份有限公司 2021-03-19 — — CN disclosed
CN-105087704-B Controllable multi-enzyme cascade reaction for synthesizing optical pure allylic epoxy ketone or alcohol 中国科学院成都生物研究所 2020-02-21 — — CN disclosed
US-20190010149-A1 SUSTAINED-RELEASE FORMULATION FOR INJECTION SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2019-01-10 — — US disclosed
US-9469630-B2 Sustained-release formulation for injection SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2016-10-18 — — US disclosed
US-20160158228-A1 SUSTAINED-RELEASE FORMULATION FOR INJECTION SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2016-06-09 — — US disclosed
EP-2629775-A1 SUSTAINED-RELEASE FORMULATION FOR INJECTION Dainippon Sumitomo Pharma Co., Ltd. (JP) 2013-08-28 — — EP disclosed
WO-2012053654-A1 SUSTAINED-RELEASE FORMULATION FOR INJECTION DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2012-04-26 — — WO disclosed
US-20120091022-A1 SUSTAINED-RELEASE FORMULATION FOR INJECTION SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2012-04-19 — — US disclosed
US-20030186400-A1 Method for producing optically active 2-hydroxycycloalkanecarboxylic acid ester SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-02 — — US disclosed
EP-1323827-A2 Method for producing optically active 2-hydroxycycloalkanecarboxylic acid ester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-02 — — EP disclosed
EP-0461526-B1 Hair treating composition KAO CORP (JP) 1995-01-25 — — EP disclosed
US-5219562-A Thioglyceryl ethers; permanent wave solutions with reduced odor and skin irritation KAO CORPORATION (JP) 1993-06-15 — — US disclosed
US-5137884-A Antibiotics MERCK & CO., INC. (US) 1992-08-11 — — US disclosed
EP-0461526-A2 Hair treating composition KAO CORPORATION (JP) 1991-12-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186400-A1 Method for producing optically active 2-hydroxycycloalkanecarboxylic acid ester HACL2, APEH, HAO2 SLC34A1 3081/4885LMNA 1919/4885KDM4E 2467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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