Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23953795 | 0.91 | ESR2 (0.32) | — | |
| SCHEMBL21236590 | 0.83 | — | — | |
| SCHEMBL21236592 | 0.81 | LMNA (0.36) | — | |
| SCHEMBL21236591 | 0.81 | CYP11B1 (0.32) | FASN | |
| SCHEMBL23953794 | 0.69 | SUV39H2 (0.37) | — | |
| SCHEMBL11115196 | 0.66 | CYP2C9 (0.36) | FASN | |
| SCHEMBL11115194 | 0.66 | CYP2C9 (0.36) | FASN | |
| SCHEMBL9402508 | 0.65 | DHODH (0.40) | — | |
| SCHEMBL9328019 | 0.65 | DHODH (0.40) | — | |
| SCHEMBL11110508 | 0.64 | HCRTR2 (0.39) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746444-B1 | CYCLOALKYL SUBSTITUTED PYRAZOLOPYRIMIDINES HAVING ACTIVITY AGAINST RSV | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2023-09-27 | — | — | EP | disclosed |
| WO-2019149734-A1 | CYCLOALKYL SUBSTITUTED PYRAZOLOPYRIMIDINES HAVING ACTIVITY AGAINST RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2019-08-08 | — | — | WO | disclosed |