Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | RARB | P10826 | 3/20 | 0.60 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289971 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL3071049 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL3086009 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL7288765 | 0.98 | ALDH1A1 (0.63) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL13739981 | 0.98 | ALDH1A1 (0.63) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL1864244 | 0.95 | ALDH1A1 (0.67) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL10497693 | 0.95 | ALDH1A1 (0.67) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL585375 | 0.95 | ALDH1A1 (0.67) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL1164373 | 0.95 | ALDH1A1 (0.67) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL1164661 | 0.95 | ALDH1A1 (0.67) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030220236-A1 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY | 2003-11-27 | — | — | US | claimed |
| EP-0561639-A1 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY (US) | 1993-09-22 | — | — | EP | claimed |
| EP-2586764-B1 | COMPOUND HAVING BRANCHED ALKYL OR BRANCHED ALKENYL, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL ELEMENT | JNC CORP (JP) | 2019-09-18 | — | — | EP | disclosed |
| EP-2468740-B1 | TETRAHYDROPYRAN COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS AND LIQUID CRYSTAL DISPLAY DEVICES | JNC CORP (JP) | 2017-08-02 | — | — | EP | disclosed |
| US-20140178606-A1 | CELLULOSE ACYLATE FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2014-06-26 | — | — | US | disclosed |
| US-8477275-B2 | Optical film and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2013-07-02 | — | — | US | disclosed |
| US-20130128359-A1 | OPTICAL FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY APPARATUS | FUJIFILM CORPORATION (JP) | 2013-05-23 | — | — | US | disclosed |
| US-8420187-B2 | Cellulose acylate composition, cellulose acylate film, and its applications | FUJIFILM CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20120092595-A1 | Optical film, polarizing plate and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2012-04-19 | — | — | US | disclosed |
| US-20120092594-A1 | OPTICAL FILM AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2012-04-19 | — | — | US | disclosed |
| US-7790744-B2 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| EP-0438754-A1 | Optically active compound, intermediate therefor, process for producing the intermediate, and liquid-crystal composition | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1991-07-31 | — | — | EP | disclosed |
| EP-0251335-B1 | HALOGENEN-SUBSTITUTED PHENYL BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM AND OPTICAL SWITCHING ELEMENT | Chisso Corporation (JP) | 1991-04-24 | — | — | EP | disclosed |
| EP-0290570-A1 | CHIRAL OR ACHIRAL CYCLIC COMPOUNDS. | MERCK PATENT GMBH (DE) | 1988-11-17 | — | — | EP | disclosed |
| US-4784791-A | LIQUID CRYSTAL COMPOUNDS FOR OPTICAL SWITCHES | CHISSO CORPORATION (JP) | 1988-11-15 | — | — | US | disclosed |
| EP-0174191-B1 | LIQUID CRYSTAL COMPOUND HAVING METHYLENEOXY GROUP AND COMPOSITION CONTAINING SAME | Chisso Corporation (JP) | 1988-07-27 | — | — | EP | disclosed |
| US-4751019-A | OPTICAL ACTIVITY | CHISSO CORPORATION (JP) | 1988-06-14 | — | — | US | disclosed |
| WO-1988003530-A1 | CHIRAL OR ACHIRAL CYCLIC COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-05-19 | — | — | WO | disclosed |
| EP-0251335-A2 | Halogenen-substituted phenyl benzyl ether derivatives, liquid crystal compositions containing them and optical switching element | Chisso Corporation (JP) | 1988-01-07 | — | — | EP | disclosed |
| US-4668427-A | LIGHT SWITCHING ELEMENT | CHISSO CORPORATION (JP) | 1987-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220236-A1 | Cyclic peptide antifungal agents and process for preparation thereof | NGLY1, HM13, PTMS | ALDH1A1 4721/4885HPGD 2068/4885LMNA 3429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.