Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | RARB | P10826 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13739981 | 1.00 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL3086009 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL2123631 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL3071049 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL7289971 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL3077169 | 0.96 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL1443663 | 0.95 | ALDH1A1 (0.69) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL1164661 | 0.93 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL1239921 | 0.93 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL585375 | 0.93 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575964-B1 | N-(BENZYL)AMINOALKYL CARBOXYLATE, PHOSPHINATES, PHOSPHONATES AND TETRAZOLES AS EDG RECEPTOR AGONISTS | MERCK & CO INC (US) | 2009-11-11 | — | — | EP | disclosed |
| US-7351725-B2 | N-(benzyl)aminoalkylcarboxylates, phosphinates, phosphonates and tetrazoles as Edg receptor agonists | MERCK & CO., INC. (US) | 2008-04-01 | — | — | US | disclosed |
| US-7351725-B2 | N-(benzyl)aminoalkylcarboxylates, phosphinates, phosphonates and tetrazoles as Edg receptor agonists | MERCK & CO., INC. (US) | 2008-04-01 | — | — | US | disclosed |
| CN-1057306-C | New polypeptide compound and a process for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-10-11 | — | — | CN | disclosed |
| EP-0644199-B1 | Cyclic antimicrobial peptides and preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5693750-A | MICROBIOCIDAL ACTION AGAINST PNEUMOCYSTIS INFECTIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| US-5569646-A | TREATMENT OF PNEUMONIA; MICROBIOCIDES, FUNGICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-29 | — | — | US | disclosed |
| EP-0644199-A1 | Cyclic antimicrobial peptides and preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |
| CN-1100104-A | New polypeptide compound and a process for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-03-15 | — | — | CN | disclosed |