Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21236759 | 0.91 | MBOAT4 (0.61) | MBOAT4 | |
| SCHEMBL22964458 | 0.83 | MBOAT4 (0.58) | MBOAT4 | |
| SCHEMBL21236924 | 0.81 | MBOAT4 (0.46) | MBOAT4 | |
| SCHEMBL21236901 | 0.78 | MBOAT4 (0.53) | MBOAT4 | |
| SCHEMBL21236760 | 0.77 | HTT (0.45) | MBOAT4 | |
| SCHEMBL22964464 | 0.76 | MBOAT4 (0.54) | MBOAT4 | |
| SCHEMBL21236903 | 0.76 | MBOAT4 (0.57) | MBOAT4 | |
| SCHEMBL21236921 | 0.76 | MBOAT4 (0.44) | MBOAT4 | |
| SCHEMBL21236700 | 0.76 | MBOAT4 (0.48) | MBOAT4 | |
| SCHEMBL21236794 | 0.73 | MBOAT4 (0.62) | MBOAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136337-B2 | Pyrazole- and indazole-substituted oxadiazolopyridine derivatives for use as ghrelin O-acyl transferase (GOAT) inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-10-05 | — | — | US | disclosed |
| US-20210040113-A1 | PYRAZOLE- AND INDAZOLE- SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2021-02-11 | — | — | US | disclosed |
| WO-2019149658-A1 | PYRAZOLE- AND INDAZOLE-SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040113-A1 | PYRAZOLE- AND INDAZOLE- SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS | GIPR, GPR119, MBOAT4 | MBOAT4 3/4885 |
| US-11136337-B2 | Pyrazole- and indazole-substituted oxadiazolopyridine derivatives for use as ghrelin O-acyl transferase (GOAT) inhibitors | GIPR, GPR119, MBOAT4 | MBOAT4 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.