Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CHUK | O15111 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18384715 | 0.85 | MAOA (0.38) | MAOACHUKACHE | |
| SCHEMBL18384582 | 0.85 | MAOA (0.38) | MAOACHUKACHE | |
| SCHEMBL18384590 | 0.78 | MAOA (0.41) | MAOACHUKMAPTPDGFRBPDGFRA | |
| SCHEMBL18384572 | 0.75 | MAOA (0.38) | MAOACHUKACHE | |
| SCHEMBL18384605 | 0.75 | CYP2A6 (0.42) | MAOACHUKMAPTACHE | |
| SCHEMBL18473250 | 0.75 | MAOA (0.38) | MAOACHUKACHE | |
| SCHEMBL18384542 | 0.75 | MAOA (0.38) | MAOACHUKACHE | |
| SCHEMBL18384711 | 0.75 | CYP2A6 (0.42) | MAOACHUKMAPTACHE | |
| SCHEMBL18384610 | 0.75 | MAOA (0.38) | MAOACHUKACHE | |
| SCHEMBL18384535 | 0.74 | KDM4E (0.39) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10934309-B2 | Tricyclic quinone derivative | SUMITOMO DAINIPPON PHARMA ONCOLOGY, INC. (US) | 2021-03-02 | — | — | US | disclosed |
| US-20190241583-A1 | NEW TRICYCLIC QUINONE DERIVATIVE | SUMITOMO DAINIPPON PHARMA ONCOLOGY, INC. | 2019-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241583-A1 | NEW TRICYCLIC QUINONE DERIVATIVE | NQO1, SQOR, SULT1E1 | MAOA 599/4885CHUK 1982/4885MAPT 3909/4885 |
| US-10934309-B2 | Tricyclic quinone derivative | NQO1, NQO2, SQOR | MAOA 540/4885CHUK 2145/4885MAPT 3904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.