Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 5/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21237487 | 0.77 | CYP11B1 (0.38) | RIPK1L3MBTL1TSHRCYP11B1CYP11B2 | |
| SCHEMBL65394 | 0.77 | ACVRL1 (0.50) | ACVRL1FGFR1FGFR3 | |
| SCHEMBL21237164 | 0.75 | ACVRL1 (0.46) | ACVRL1PIK3CDFGFR1FGFR3PLK4 | |
| SCHEMBL65572 | 0.75 | ACVRL1 (0.45) | ACVRL1PIK3CD | |
| SCHEMBL21237594 | 0.71 | CSNK2A2 (0.40) | RIPK1PIK3CDCSNK2A2CSNK2A1 | |
| SCHEMBL65573 | 0.69 | ACVRL1 (0.38) | ACVRL1RIPK1PIK3CDFGFR1CSNK2A2 | |
| SCHEMBL66408 | 0.69 | PIK3CD (0.37) | ACVRL1RIPK1PIK3CDCSNK2A2CSNK2A1 | |
| SCHEMBL66503 | 0.68 | ALDH1A1 (0.43) | ACVRL1PIK3CDKDRALDH1A1 | |
| SCHEMBL14537333 | 0.67 | NTRK1 (0.44) | PIK3CDFGFR1FGFR3PLK4AURKA | |
| SCHEMBL14531415 | 0.67 | ACVRL1 (0.43) | ACVRL1PIK3CDFGFR1FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149114-A1 | PREPARATION AND USE OF COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT OR COMPOSITION THEREOF | 深圳铂立健医药有限公司 | 2019-08-08 | — | — | WO | disclosed |