⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15744688 | 0.77 | MGAM (0.39) | — | |
| SCHEMBL9706629 | 0.77 | — | — | |
| SCHEMBL13369568 | 0.74 | — | — | |
| SCHEMBL21266182 | 0.74 | MAPT (0.31) | — | |
| SCHEMBL12872174 | 0.73 | — | — | |
| SCHEMBL318974 | 0.73 | — | — | |
| SCHEMBL18699251 | 0.73 | — | — | |
| SCHEMBL318975 | 0.73 | — | — | |
| SCHEMBL22193173 | 0.72 | LMNA (0.35) | — | |
| SCHEMBL24006874 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210115101-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE | MODERNATX, INC. | 2021-04-22 | — | — | US | disclosed |
| US-10577403-B2 | Modified polynucleotides for the production of secreted proteins | MODERNATX, INC. (US) | 2020-03-03 | — | — | US | disclosed |
| US-20190315824-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF SECRETED PROTEINS | MODERNATX, INC. (US) | 2019-10-17 | — | — | US | disclosed |
| US-20190240351-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS | MODERNATX, INC. | 2019-08-08 | — | — | US | disclosed |