Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11949181 | 0.78 | MGAM (0.36) | MGAMGAASIMGAM2HTT | |
| SCHEMBL22193173 | 0.78 | LMNA (0.35) | ALDH1A1TDP1KDM4ERECQLTSHR | |
| SCHEMBL21237871 | 0.77 | — | — | |
| SCHEMBL318975 | 0.73 | — | — | |
| SCHEMBL12872174 | 0.73 | — | — | |
| SCHEMBL18699251 | 0.73 | — | — | |
| SCHEMBL318974 | 0.73 | — | — | |
| Butanedione SCHEMBL14236845 | 0.70 | TSHR (0.58) | MGAMGAASIMGAM2HTT | |
| SCHEMBL10389469 | 0.69 | MGAM (0.56) | MGAMGAASIMGAM2HTT | |
| SCHEMBL1608 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780833-B2 | Emetine derivatives, prodrugs containing same, and methods of treating conditions using same | HOWARD UNIVERSITY (US) | 2023-10-10 | — | — | US | disclosed |
| US-20170190700-A1 | Emetine Derivatives, Prodrugs Containing Same, And Methods Of Treating Conditions Using Same | BAKARE OLADAPO (US) | 2017-07-06 | — | — | US | disclosed |
| US-9492560-B2 | Emetine derivatives, prodrugs containing same, and methods of treating conditions using same | HOWARD UNIVERSITY | 2016-11-15 | — | — | US | disclosed |
| US-20140148377-A1 | Emetine Derivatives, Prodrugs Containing Same, And Methods Of Treating Conditions Using Same | HOWARD UNIVERSITY | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190700-A1 | Emetine Derivatives, Prodrugs Containing Same, And Methods Of Treating Conditions Using Same | EML4, MCL1, ERAP2 | MGAM 893/4885GAA 2173/4885SI 1343/4885 |
| US-11780833-B2 | Emetine derivatives, prodrugs containing same, and methods of treating conditions using same | EML4, MCL1, ERAP2 | MGAM 893/4885GAA 2173/4885SI 1343/4885 |
| US-20140148377-A1 | Emetine Derivatives, Prodrugs Containing Same, And Methods Of Treating Conditions Using Same | EML4, MCL1, ERAP2 | MGAM 893/4885GAA 2173/4885SI 1343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.