Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 12/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17455982 | 0.82 | HPGD (0.51) | RBP4ALDH1A1 | |
| SCHEMBL17455940 | 0.78 | NAMPT (0.46) | RBP4SCDKDM4EALDH1A1 | |
| SCHEMBL17456017 | 0.77 | NAMPT (0.53) | ALDH1A1 | |
| SCHEMBL17456064 | 0.75 | RBP4 (0.47) | RBP4SCD | |
| SCHEMBL17456003 | 0.75 | RBP4 (0.41) | RBP4SCDTDP1KDM4EALDH1A1 | |
| SCHEMBL17455922 | 0.75 | ALDH1A1 (0.43) | RBP4SCDTDP1KDM4EALDH1A1 | |
| SCHEMBL17455927 | 0.73 | RBP4 (0.53) | RBP4ALDH1A1 | |
| SCHEMBL17455956 | 0.72 | TMEM97 (0.51) | RBP4ALDH1A1 | |
| SCHEMBL17456006 | 0.71 | NAMPT (0.46) | RBP4 | |
| SCHEMBL17505977 | 0.71 | ERBB2 (0.44) | RBP4SCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982666-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-07 | — | — | EP | disclosed |