Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 8/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | FPR1 | P21462 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21239460 | 1.00 | FPR2 (0.77) | FPR2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL21239537 | 1.00 | FPR2 (0.77) | FPR2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL14948924 | 0.88 | FPR2 (0.69) | FPR2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL14903124 | 0.87 | FPR2 (1.00) | FPR2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL16738195 | 0.87 | FPR2 (0.71) | FPR2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL21239525 | 0.85 | FPR2 (0.57) | FPR2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL21239550 | 0.85 | FPR2 (0.57) | FPR2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL21239527 | 0.85 | FPR2 (0.57) | FPR2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL21239463 | 0.85 | FPR2 (0.57) | FPR2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL21239484 | 0.85 | FPR2 (0.57) | FPR2KMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206716-A1 | UREA DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-07-08 | — | — | US | claimed |
| EP-3524240-A1 | UREA DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-08-14 | — | — | EP | claimed |
| CN-109843283-A | Urea derivative | 第一三共株式会社 | 2019-06-04 | — | — | CN | claimed |
| CN-109843283-B | Urea derivatives | 第一三共株式会社 | 2022-08-30 | — | — | CN | disclosed |
| US-20220144765-A1 | UREA DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-05-12 | — | — | US | disclosed |
| US-20220144765-A1 | UREA DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-05-12 | — | — | US | disclosed |
| US-20210206716-A1 | UREA DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-07-08 | — | — | US | disclosed |
| US-20210206716-A1 | UREA DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-07-08 | — | — | US | disclosed |
| US-10968169-B2 | Urea derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-04-06 | — | — | US | disclosed |
| US-10968169-B2 | Urea derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-04-06 | — | — | US | disclosed |
| EP-3524240-A1 | UREA DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-08-14 | — | — | EP | disclosed |
| CN-109843283-A | Urea derivative | 第一三共株式会社 | 2019-06-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206716-A1 | UREA DERIVATIVE | IDO1, IDO2, TPH1 | FPR2 1882/4885KMT2A 2283/4885MEN1 4040/4885 |
| US-10968169-B2 | Urea derivative | IDO1, IDO2, UTS2R | FPR2 2003/4885KMT2A 2627/4885MEN1 3957/4885 |
| US-20220144765-A1 | UREA DERIVATIVE | IDO1, IDO2, TPH1 | FPR2 1882/4885KMT2A 2283/4885MEN1 4040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.