Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24368363 | 0.86 | — | — | |
| SCHEMBL21940976 | 0.85 | — | — | |
| SCHEMBL24665405 | 0.84 | CYP2D6 (0.30) | — | |
| SCHEMBL20887275 | 0.84 | TSHR (0.38) | — | |
| SCHEMBL11870424 | 0.84 | OPRM1 (0.42) | KDM2BOPRM1SPHK1 | |
| SCHEMBL22024185 | 0.84 | TSHR (0.38) | — | |
| SCHEMBL3411263 | 0.84 | OPRM1 (0.42) | KDM2BOPRM1SPHK1 | |
| SCHEMBL9070252 | 0.82 | OPRM1 (0.44) | KDM2BOPRM1SPHK1 | |
| SCHEMBL19797928 | 0.79 | KDM2B (0.34) | KDM2B | |
| SCHEMBL24355086 | 0.78 | OPRM1 (0.38) | KDM2BOPRM1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968316-B1 | 2-HYDROXY-1-{4-[(4-PHENYLPHENYL)CARBONYL]PIPERAZIN-1-YL}ETHAN-1-ONE DERIVATIVES AND RELATED COMPOUNDS AS FATTY ACID SYNTHASE (FASN) INHIBITORS FOR THE TREATMENT OF CANCER | FORMA THERAPEUTICS INC (US) | 2019-08-07 | — | — | EP | disclosed |