⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24368363 | 0.98 | — | — | |
| SCHEMBL24665405 | 0.96 | CYP2D6 (0.30) | — | |
| SCHEMBL22024185 | 0.85 | TSHR (0.38) | — | |
| SCHEMBL20887275 | 0.85 | TSHR (0.38) | — | |
| SCHEMBL21240086 | 0.85 | KDM2B (0.32) | — | |
| SCHEMBL21166136 | 0.80 | GNAO1 (0.37) | — | |
| SCHEMBL20243856 | 0.80 | GNAO1 (0.37) | — | |
| SCHEMBL24805431 | 0.80 | L3MBTL1 (0.34) | — | |
| SCHEMBL24822838 | 0.80 | TSHR (0.33) | — | |
| SCHEMBL21191763 | 0.80 | L3MBTL1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11208655-B2 | Functionally-modified oligonucleotides and subunits thereof | SAREPTA THERAPEUTICS, INC. (US) | 2021-12-28 | — | — | US | disclosed |
| US-20200115709-A1 | Functionally-Modified Oligonucleotides And Subunits Thereof | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2020-04-16 | — | — | US | disclosed |