Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27296746 | 0.84 | MAPT (0.45) | MAPTKDM4ENOTUMGPR35MEN1 | |
| SCHEMBL30410929 | 0.78 | CSNK2A1 (0.48) | MAPTNOTUMCSNK2A1MEN1KMT2A | |
| SCHEMBL23062945 | 0.78 | CSNK2A1 (0.53) | MAPTNOTUMCSNK2A1MEN1KMT2A | |
| SCHEMBL16421197 | 0.78 | CSNK2A1 (0.48) | MAPTNOTUMCSNK2A1MEN1KMT2A | |
| SCHEMBL9244562 | 0.77 | KDM4E (0.49) | MAPTKDM4ENOTUMCSNK2A1MEN1 | |
| SCHEMBL3392534 | 0.77 | KDM4E (0.58) | KDM4ENOTUMGPR35CSNK2A1MEN1 | |
| SCHEMBL30280884 | 0.76 | CAMKK2 (0.39) | MAPTKDM4ENOTUMGPR35MEN1 | |
| SCHEMBL30281103 | 0.75 | MAPT (0.37) | MAPTKDM4ENOTUMGPR35MEN1 | |
| SCHEMBL27733843 | 0.75 | MAPT (0.50) | MAPTKDM4ENOTUMGPR35MEN1 | |
| SCHEMBL4969775 | 0.74 | NOTUM (0.49) | MAPTKDM4ENOTUMGPR35MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |