Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
| ▸ | CAMKK1 | Q8N5S9 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30281011 | 0.83 | OPRK1 (0.39) | KDM4E | |
| SCHEMBL30280752 | 0.80 | ACMSD (0.35) | CAMKK2MAPTACMSDCAMKK1NOTUM | |
| SCHEMBL30281103 | 0.79 | MAPT (0.37) | CAMKK2MAPTACMSDCAMKK1KDM4E | |
| SCHEMBL30280904 | 0.76 | PDK2 (0.41) | MAPTKDM4E | |
| SCHEMBL21241026 | 0.76 | MAPT (0.46) | CAMKK2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL30281000 | 0.76 | HSD17B10 (0.39) | CAMKK2MAPTKDM4EKMT2ATDP1 | |
| SCHEMBL28071071 | 0.76 | BRD4 (0.41) | CAMKK2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL27483638 | 0.75 | ACMSD (0.41) | CAMKK2MAPTACMSDCAMKK1KDM4E | |
| SCHEMBL27296746 | 0.75 | MAPT (0.45) | CAMKK2MAPTACMSDKDM4EMEN1 | |
| SCHEMBL12488784 | 0.74 | MAPT (0.38) | CAMKK2MAPTACMSDNOTUMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |