Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2044641 | 0.84 | MEN1 (0.59) | MEN1KMT2ANPC1TSHRRAB9A | |
| SCHEMBL13729565 | 0.82 | MEN1 (0.73) | MEN1KMT2ANPC1TSHRRAB9A | |
| SCHEMBL13730829 | 0.80 | KMT2A (0.44) | MEN1KMT2ANPC1TSHRRAB9A | |
| SCHEMBL13730860 | 0.77 | KMT2A (0.41) | MEN1KMT2ANPC1TSHRRAB9A | |
| SCHEMBL13729611 | 0.77 | MEN1 (0.48) | MEN1KMT2ANPC1TSHRRAB9A | |
| SCHEMBL13729592 | 0.76 | BCAT2 (0.55) | MEN1KMT2ANPC1TSHRRAB9A | |
| SCHEMBL13730831 | 0.72 | MAP4K4 (0.42) | MEN1KMT2AALDH1A1MAP4K4MRGPRX1 | |
| SCHEMBL10220140 | 0.70 | NNMT (0.41) | MEN1KMT2ANPC1TSHRRAB9A | |
| SCHEMBL13729431 | 0.70 | KMT2A (0.46) | MEN1KMT2ANPC1TSHRRAB9A | |
| SCHEMBL27606810 | 0.69 | MEN1 (0.47) | MEN1KMT2ANPC1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |