Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241202 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPTRAB9AHCRTR2 | |
| SCHEMBL82719 | 0.76 | PDE10A (0.46) | KDM4EALDH1A1HSD17B10TSHRPDE10A | |
| SCHEMBL25063728 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL11929545 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL19599653 | 0.73 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10MAPTPDE10A | |
| SCHEMBL10265614 | 0.73 | ALDH1A1 (0.49) | KDM4EALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL20381746 | 0.72 | MAPT (0.44) | KDM4EALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL832761 | 0.72 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10MAPTPDE10A | |
| SCHEMBL15489125 | 0.72 | APP (0.43) | KDM4EALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL11929549 | 0.72 | ALDH1A1 (0.45) | KDM4EALDH1A1HSD17B10TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |