Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | WEE1 | P30291 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241067 | 0.79 | KDM4E (0.41) | ALDH1A1TSHRMAPTHCRTR2SMN1; SMN2 | |
| SCHEMBL8278931 | 0.79 | UHRF1 (0.42) | ALDH1A1MAPTHCRTR2SMN1; SMN2NPC1 | |
| SCHEMBL12017658 | 0.77 | UHRF1 (0.43) | ALDH1A1TSHRMAPTHCRTR2SMN1; SMN2 | |
| SCHEMBL17707978 | 0.74 | UHRF1 (0.43) | ALDH1A1 | |
| SCHEMBL10187322 | 0.74 | CRHR1 (0.44) | ALDH1A1TSHRMAPTNPC1L3MBTL1 | |
| SCHEMBL12017657 | 0.74 | KMT2A (0.44) | ALDH1A1HCRTR2SMN1; SMN2 | |
| SCHEMBL18214846 | 0.73 | PLAU (0.42) | ALDH1A1SMN1; SMN2MAPK10NPC1L3MBTL1 | |
| SCHEMBL21384005 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HCRTR2SMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL28909873 | 0.73 | PLAU (0.39) | ALDH1A1HCRTR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28872269 | 0.72 | UHRF1 (0.45) | ALDH1A1SMN1; SMN2MAPK10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |