Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241279 | 1.00 | FKBP1A (0.70) | FKBP1A | |
| SCHEMBL29692766 | 0.97 | FKBP1A (0.69) | FKBP1A | |
| SCHEMBL21241272 | 0.90 | FKBP1A (0.61) | FKBP1A | |
| SCHEMBL21241277 | 0.90 | FKBP1A (0.61) | FKBP1A | |
| SCHEMBL23485251 | 0.89 | FKBP1A (0.60) | FKBP1A | |
| SCHEMBL21241599 | 0.87 | FKBP1A (0.69) | FKBP1A | |
| SCHEMBL21241498 | 0.87 | FKBP1A (0.69) | FKBP1A | |
| SCHEMBL29692931 | 0.87 | FKBP1A (0.64) | FKBP1A | |
| SCHEMBL25755707 | 0.87 | FKBP1A (0.60) | FKBP1A | |
| SCHEMBL9200383 | 0.86 | PRCP (0.61) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746440-B1 | PIPECOLIC ESTERS FOR INHIBITION OF THE PROTEASOME | UNIV TEXAS (US) | 2023-07-05 | — | — | EP | disclosed |
| US-11345659-B2 | Pipecolic esters for inhibition of the proteasome | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-05-31 | — | — | US | disclosed |
| US-20210002220-A1 | PIPECOLIC ESTERS FOR INHIBITION OF THE PROTEASOME | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2021-01-07 | — | — | US | disclosed |
| WO-2019152527-A1 | PIPECOLIC ESTERS FOR INHIBITION OF THE PROTEASOME | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345659-B2 | Pipecolic esters for inhibition of the proteasome | PSMG3, PSME3, PSMC1 | FKBP1A 1719/4885 |
| US-20210002220-A1 | PIPECOLIC ESTERS FOR INHIBITION OF THE PROTEASOME | PSMG3, PSME3, PSMC1 | FKBP1A 1719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.