Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 3/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680894 | 0.80 | KDM4E (0.34) | KDM4EALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL28208516 | 0.77 | KDM4E (0.38) | KDM4EMAPTMEN1PABPC1KMT2A | |
| SCHEMBL27858863 | 0.77 | KDM4E (0.37) | KDM4EALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL27660249 | 0.75 | TP53 (0.33) | KDM4EALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL1603208 | 0.74 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL28158103 | 0.72 | KDM4E (0.30) | KDM4EALDH1A1HPGD | |
| Water SCHEMBL28878288 | 0.72 | ALDH1A1 (0.36) | KDM4EALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL826780 | 0.65 | MAOB (0.45) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL28158548 | 0.64 | KDM4E (0.33) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL23204805 | 0.64 | KDM4E (0.41) | KDM4EALDH1A1HPGDMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |