Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.53 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.53 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.53 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.53 |
| ▸ | CBFB | Q13951 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 2/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12948580 | 0.88 | NPC1 (0.66) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL6433457 | 0.83 | NPC1 (0.53) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL24117372 | 0.79 | CYP2A6 (0.56) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL20292801 | 0.77 | MALT1 (0.58) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL17919672 | 0.76 | TDP1 (0.64) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL29728201 | 0.76 | NPC1 (0.77) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL1538297 | 0.76 | NPC1 (0.77) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL16888859 | 0.75 | TDP1 (0.62) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL20292850 | 0.75 | KDM4E (0.45) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL2175124 | 0.74 | NPC1 (0.67) | NPC1RAB9AKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |