Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20390565 | 0.79 | ADRA2A (0.42) | NPSR1ADRA2AADRA2BADRA2CKCNQ3 | |
| SCHEMBL1013703 | 0.78 | ALDH1A1 (0.54) | NPSR1KCNQ3KCNQ2HDAC1HDAC6 | |
| SCHEMBL16502201 | 0.76 | NPSR1 (0.38) | NPSR1ADRA2AADRA2BADRA2CKCNQ3 | |
| SCHEMBL19533192 | 0.73 | TDP1 (0.46) | NPSR1ALDH1A1MAPTNPC1GAA | |
| SCHEMBL15426953 | 0.73 | — | — | |
| SCHEMBL31335160 | 0.73 | — | — | |
| SCHEMBL14234945 | 0.72 | NPSR1 (0.43) | NPSR1ADRA2AADRA2BADRA2CKCNQ3 | |
| SCHEMBL22137313 | 0.72 | NPSR1 (0.43) | NPSR1ADRA2AADRA2BADRA2CKCNQ3 | |
| SCHEMBL18463191 | 0.71 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTNPC1GAA | |
| SCHEMBL21392142 | 0.71 | NPSR1 (0.47) | NPSR1ADRA2AADRA2BADRA2CKCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |