Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | PAK4 | O96013 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399098 | 0.80 | CCR1 (0.48) | HPGDCHRNA7PIM1CCR1CCR5 | |
| SCHEMBL25693514 | 0.78 | NOTUM (0.54) | HPGDNOTUM | |
| SCHEMBL14211873 | 0.77 | HPGDS (0.37) | HPGDHPGDSCHRNA7LTA4HBRD4 | |
| SCHEMBL14209412 | 0.76 | HPGDS (0.46) | HPGDHPGDSLTA4HBRD4NOTUM | |
| SCHEMBL30210858 | 0.76 | CCR1 (0.61) | HPGDHPGDSCHRNA7LTA4HBRD4 | |
| SCHEMBL21695756 | 0.75 | PIM1 (0.33) | CHRNA7PIM1CCR1CCR5CCR8 | |
| SCHEMBL13380084 | 0.75 | LMNA (0.46) | HPGDSLTA4HBRD4NOTUMPDE2A | |
| SCHEMBL9263374 | 0.74 | NOTUM (0.53) | HPGDHPGDSCHRNA7LTA4HBRD4 | |
| SCHEMBL13380088 | 0.73 | AKR1C3 (0.38) | HPGDBRD4CTSA | |
| SCHEMBL19362627 | 0.73 | CCR1 (0.41) | HPGDCHRNA7PIM1CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |