Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.57 |
| ▸ | CCR5 | P51681 | 1/20 | 0.57 |
| ▸ | CCR8 | P51685 | 1/20 | 0.57 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24419756 | 0.84 | IDH1 (0.43) | CCR1CCR5CCR8MEN1KMT2A | |
| SCHEMBL10513619 | 0.80 | NPC1 (0.46) | CCR1CCR5CCR8KMT2AKDM4E | |
| SCHEMBL16487535 | 0.75 | SMN1; SMN2 (0.42) | MEN1KMT2AKDM4EALDH1A1THRB | |
| SCHEMBL181893 | 0.75 | CCR1 (1.00) | CCR1CCR5CCR8UHRF1CYP2A6 | |
| SCHEMBL29397106 | 0.75 | CCR1 (1.00) | CCR1CCR5CCR8UHRF1CYP2A6 | |
| SCHEMBL16200245 | 0.74 | HTT (0.46) | UHRF1MEN1KMT2AIDH1HTT | |
| SCHEMBL13610027 | 0.74 | KDM4E (0.55) | CCR1CCR5CCR8MEN1KMT2A | |
| SCHEMBL15664136 | 0.73 | CCR1 (0.94) | CCR1CCR5CCR8UHRF1CYP2A6 | |
| Hydrochloric Acid SCHEMBL5549447 | 0.73 | CCR1 (0.94) | CCR1CCR5CCR8UHRF1CYP2A6 | |
| SCHEMBL6820852 | 0.73 | CCR1 (0.94) | CCR1CCR5CCR8UHRF1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |