Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 7/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GSR | P00390 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241641 | 0.87 | MAPT (0.52) | MAPTALOX15HPNSIRT5VCAM1 | |
| SCHEMBL21241539 | 0.86 | ALOX15 (0.56) | MAPTALOX15HPNSIRT5VCAM1 | |
| SCHEMBL30341728 | 0.85 | ALOX15 (0.70) | MAPTALOX15HPNSIRT5VCAM1 | |
| SCHEMBL21241681 | 0.85 | ALOX15 (0.70) | MAPTALOX15HPNSIRT5VCAM1 | |
| SCHEMBL21222714 | 0.85 | ALOX15 (0.70) | MAPTALOX15HPNSIRT5VCAM1 | |
| SCHEMBL21241548 | 0.81 | CA2 (0.45) | MAPTALOX15HPNSIRT5CA2 | |
| SCHEMBL21241549 | 0.80 | MAPT (0.45) | MAPTALOX15HPNSIRT5VCAM1 | |
| SCHEMBL22963973 | 0.76 | ALOX15 (0.66) | MAPTALOX15HPNSIRT5VCAM1 | |
| SCHEMBL22964078 | 0.76 | ALOX15 (0.51) | MAPTALOX15HPNSIRT5VCAM1 | |
| SCHEMBL4811810 | 0.74 | CYP2C9 (0.57) | MAPTALOX15HPNSIRT5VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149091-A1 | PROBUCOL DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 北京德默高科医药技术有限公司 | 2019-08-08 | — | — | WO | disclosed |