Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26296615 | 0.87 | FKBP1A (0.49) | ACEALDH1A1FKBP1APREPLTA4H | |
| SCHEMBL25755557 | 0.84 | FKBP1A (0.51) | FKBP1A | |
| SCHEMBL23675904 | 0.84 | ACE (0.48) | ACESMN1; SMN2FKBP1APREPNPC1 | |
| SCHEMBL21241447 | 0.79 | FKBP1A (0.59) | FKBP1A | |
| SCHEMBL25756049 | 0.79 | FKBP1A (0.59) | FKBP1A | |
| SCHEMBL17171345 | 0.78 | SLC1A3 (0.38) | SMN1; SMN2FKBP1ANPC1RAB9AAGTR2 | |
| SCHEMBL22139439 | 0.77 | PREP (0.60) | PREPCTRB1 | |
| SCHEMBL9436228 | 0.76 | ACE (0.67) | ACELTA4H | |
| SCHEMBL5732638 | 0.76 | ACE (0.67) | ACELTA4H | |
| SCHEMBL5733034 | 0.76 | ACE (0.67) | ACELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152527-A1 | PIPECOLIC ESTERS FOR INHIBITION OF THE PROTEASOME | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-08-08 | — | — | WO | disclosed |