SCHEMBL25756049

SCHEMBL25756049

O=C(OCCCc1ccccc1)[C@@H]1CCCCN1C(O)OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21241447 1.00 FKBP1A (0.59) FKBP1A
SCHEMBL25755557 0.90 FKBP1A (0.51) FKBP1A
SCHEMBL25755871 0.81 FKBP1A (0.59) FKBP1A
SCHEMBL25755801 0.81 FKBP1A (0.59) FKBP1A
SCHEMBL21241271 0.80 FKBP1A (0.70) FKBP1A
SCHEMBL21241279 0.80 FKBP1A (0.70) FKBP1A
SCHEMBL26296615 0.79 FKBP1A (0.49) FKBP1A
SCHEMBL21241445 0.79 ACE (0.45) FKBP1A
SCHEMBL29692766 0.76 FKBP1A (0.69) FKBP1A
SCHEMBL5966005 0.75 FKBP1A (0.81) FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3746440-B1 PIPECOLIC ESTERS FOR INHIBITION OF THE PROTEASOME UNIV TEXAS (US) 2023-07-05 EP disclosed