Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241945 | 0.90 | MAPT (0.53) | ELOVL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL21241834 | 0.88 | MAPT (0.51) | ELOVL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL21241931 | 0.87 | MAPT (0.55) | ELOVL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL21241901 | 0.87 | MAPT (0.48) | ELOVL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL21225282 | 0.83 | MAPT (0.58) | ELOVL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL21242057 | 0.82 | MAPT (0.58) | ELOVL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL21224313 | 0.82 | MAPT (0.53) | ELOVL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL21225263 | 0.81 | KDM4A (0.62) | ELOVL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL21224424 | 0.81 | MAPT (0.52) | ELOVL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL21241928 | 0.81 | SCD (0.60) | ELOVL1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152437-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2019-08-08 | — | — | WO | disclosed |