Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.47 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241854 | 0.94 | MAPT (0.48) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21242061 | 0.93 | POLB (0.52) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL21241789 | 0.92 | MAPT (0.47) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL21241795 | 0.91 | MAPT (0.45) | MAPTMEN1KMT2AALDH1A1ELOVL1 | |
| SCHEMBL21241945 | 0.89 | MAPT (0.53) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21241981 | 0.89 | ADORA3 (0.54) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL21241887 | 0.88 | SIRT5 (0.41) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL21241888 | 0.88 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL21241834 | 0.88 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21241835 | 0.87 | ELOVL1 (0.52) | MAPTMEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152437-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2019-08-08 | — | — | WO | disclosed |