Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.48 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241945 | 0.90 | MAPT (0.53) | MAPTMEN1KMT2AELOVL1ALDH1A1 | |
| SCHEMBL21241835 | 0.88 | ELOVL1 (0.52) | MAPTMEN1KMT2AELOVL1ALDH1A1 | |
| SCHEMBL21241931 | 0.88 | MAPT (0.55) | MAPTMEN1KMT2AELOVL1ALDH1A1 | |
| SCHEMBL21241901 | 0.85 | MAPT (0.48) | MAPTMEN1KMT2AELOVL1ALDH1A1 | |
| SCHEMBL21224313 | 0.82 | MAPT (0.53) | MAPTMEN1KMT2AELOVL1ALDH1A1 | |
| SCHEMBL21242057 | 0.82 | MAPT (0.58) | MAPTMEN1KMT2AELOVL1ALDH1A1 | |
| SCHEMBL21241854 | 0.82 | MAPT (0.48) | MAPTMEN1KMT2AELOVL1ALDH1A1 | |
| SCHEMBL21224641 | 0.82 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL21224424 | 0.82 | MAPT (0.52) | MAPTMEN1KMT2AELOVL1ALDH1A1 | |
| SCHEMBL21225263 | 0.82 | KDM4A (0.62) | MAPTMEN1KMT2AELOVL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152437-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2019-08-08 | — | — | WO | disclosed |