SCHEMBL2124198

SCHEMBL2124198

COC(=O)C(C)n1cccc1C(=S)S

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
ALDH1A1 P00352 1/20 0.35
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.34
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
MAOB P27338 1/20 0.33
POLB P06746 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TP53 P04637 1/20 0.32
CYP26A1 O43174 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6384170 0.73 CYP1A2 (0.40) CYP1A2CYP3A4CYP2C9CYP2C19RECQL
SCHEMBL2126811 0.72 FPR2 (0.35) ALDH1A1RECQLPOLBNPSR1
SCHEMBL27546454 0.71 ELANE (0.39) CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1
SCHEMBL952143 0.71 ELANE (0.39) CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1
SCHEMBL38659645 0.71 POLB (0.37) ALDH1A1KMT2APTGS2POLBNPSR1
SCHEMBL4884851 0.71 CYP1A2 (0.40) CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1
SCHEMBL26205734 0.67 MAPK1 (0.43) CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1
SCHEMBL2182449 0.66 NR3C2 (0.53) CYP1A2CYP3A4CYP2C19KMT2A
SCHEMBL15125266 0.65 MAPK1 (0.48) CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1
SCHEMBL19063285 0.65 MAPK1 (0.48) CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120130008-A1 POLYCHLOROPRENE, PROCESS FOR PRODUCTION OF SAME, AND ADHESIVES CONTAINING SAME DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2012-05-24 US disclosed
EP-2444427-A1 POLYCHLOROPRENE, PROCESS FOR PRODUCTION OF SAME, AND ADHESIVES CONTAINING SAME Denki Kagaku Kogyo Kabushiki Kaisha (JP) 2012-04-25 EP disclosed