SCHEMBL21242220

SCHEMBL21242220

O=COc1ccc(/N=N/c2ccc(/C=C/c3ccc(/N=N/c4ccc(OC=O)cc4)cc3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.36
RELA Q04206 2/20 0.35
TRPA1 O75762 1/20 0.35
ELANE P08246 1/20 0.35
PTGS2 P35354 4/20 0.34
CYP1A2 P05177 3/20 0.34
CYP1A1 P04798 3/20 0.34
CYP1B1 Q16678 3/20 0.34
ESR1 P03372 2/20 0.34
TTR P02766 2/20 0.34
ALOX5 P09917 2/20 0.34
ABL1 P00519 1/20 0.34
ABCB1 P08183 1/20 0.34
BCR P11274 1/20 0.34
CYP19A1 P11511 1/20 0.34
NQO2 P16083 1/20 0.34
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
AHR P35869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21242468 0.83 ELANE (0.37) ELANEPTGS2SMN1; SMN2ALDH1A1MEN1
SCHEMBL3791384 0.82 ALDH1A1 (0.50) TRPA1ELANECYP19A1KDM4ESMN1; SMN2
SCHEMBL521733 0.82 ALDH1A1 (0.50) TRPA1ELANECYP19A1KDM4ESMN1; SMN2
SCHEMBL25677973 0.80 KMT2A (0.48) RELAELANEESR1LMNAMEN1
SCHEMBL4570682 0.80 MAPT (0.46) RELAELANEPTGS2ALOX5CYP3A4
SCHEMBL27570572 0.79 TRPA1 (0.57) RELATRPA1CYP1A2ALOX5CYP19A1
SCHEMBL19129034 0.78 ELANE (0.36) ELANEPTGS2CYP1A2SMN1; SMN2ALDH1A1
SCHEMBL28231036 0.76 NPC1 (0.60) HDAC1CYP1A2CYP1A1CYP1B1ALOX5
SCHEMBL19769299 0.76 MAPK1 (0.53) KDM4ESMN1; SMN2TP53ALDH1A1CYP2A6
SCHEMBL16769639 0.76 TRPA1 (0.58) TRPA1KDM4ESMN1; SMN2TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10442931-B2 Dye compound, composition comprising dye compound, and display device using dye compound SAMSUNG DISPLAY CO. LTD. (KR) 2019-10-15 US disclosed
EP-3412734-B1 DYE COMPOUND, COMPOSITION COMPRISING THE DYE COMPOUND, AND DISPLAY DEVICE USING THE DYE COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2019-08-07 EP disclosed