SCHEMBL21242477

SCHEMBL21242477

Nc1ncc(-c2cnc(N)s2)s1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.55
BACE1 P56817 1/20 0.54
CSNK2A1 P68400 1/20 0.50
ALDH1A1 P00352 5/20 0.46
MAPT P10636 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
MYC P01106 1/20 0.43
WDR5 P61964 1/20 0.43
LIMK1 P53667 1/20 0.42
KDM4E B2RXH2 1/20 0.41
TP53 P04637 1/20 0.41
ADORA3 P0DMS8 1/20 0.38
SLC6A3 Q01959 1/20 0.38
EPHX2 P34913 1/20 0.38
MAPK14 Q16539 1/20 0.37
HSD17B10 Q99714 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21242243 0.85 BACE1 (0.44) NOS1BACE1CSNK2A1ALDH1A1MAPT
SCHEMBL21242190 0.80 ALDH1A1 (0.46) NOS1BACE1CSNK2A1ALDH1A1MAPT
SCHEMBL7692798 0.80 MAPT (0.50) NOS1BACE1CSNK2A1ALDH1A1MAPT
SCHEMBL956185 0.80 ALDH1A1 (0.52) BACE1CSNK2A1ALDH1A1MAPTSMN1; SMN2
SCHEMBL749709 0.80 CSNK2A1 (0.46) NOS1BACE1CSNK2A1ALDH1A1MAPT
SCHEMBL69900 0.78 CSNK2A1 (0.62) BACE1CSNK2A1ALDH1A1MAPTSMN1; SMN2
SCHEMBL16526019 0.78 CSNK2A1 (0.49) NOS1BACE1CSNK2A1ALDH1A1MAPT
Bromide SCHEMBL22834317 0.77 CSNK2A1 (0.61) BACE1CSNK2A1ALDH1A1MAPTSMN1; SMN2
SCHEMBL5960025 0.77 CSNK2A1 (0.56) NOS1BACE1CSNK2A1ALDH1A1MAPT
SCHEMBL28231694 0.77 ALDH1A1 (0.55) NOS1BACE1CSNK2A1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3306690-B1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2022-09-07 EP disclosed
EP-3412734-B1 DYE COMPOUND, COMPOSITION COMPRISING THE DYE COMPOUND, AND DISPLAY DEVICE USING THE DYE COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2019-08-07 EP disclosed