Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27797508 | 0.83 | HSD17B10 (0.36) | NPC1RAB9ASMN1; SMN2MTNR1AHSD17B10 | |
| SCHEMBL667429 | 0.82 | SMN1; SMN2 (0.37) | NPC1RAB9ASMN1; SMN2TP53GLA | |
| SCHEMBL668079 | 0.81 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2TP53GLA | |
| SCHEMBL1535936 | 0.78 | MTNR1A (0.32) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10354177 | 0.78 | MTNR1A (0.32) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL668910 | 0.76 | MTNR1A (0.40) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL19380554 | 0.76 | BAZ2B (0.46) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL19380488 | 0.74 | MLYCD (0.39) | NPC1RAB9ASMN1; SMN2TP53GLA | |
| SCHEMBL19380489 | 0.72 | POLB (0.38) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL19112080 | 0.72 | TRPV1 (0.33) | NPC1RAB9ASMN1; SMN2TP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3219204-B1 | MUTANT RECEPTORS AND THEIR USE IN A NUCLEAR RECEPTOR-BASED INDUCIBLE GENE EXPRESSION SYSTEM | INTREXON CORP (US) | 2019-08-07 | — | — | EP | disclosed |