Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2125823 | 0.91 | HTT (0.46) | HTTKMT2AMEN1USP2MAOA | |
| SCHEMBL2885668 | 0.86 | HTT (0.45) | HTTKMT2AMEN1USP2MAOA | |
| SCHEMBL1423891 | 0.78 | HTT (0.48) | HTTKMT2AMEN1USP2MAOA | |
| SCHEMBL28256758 | 0.77 | HTT (0.45) | HTTKMT2AMEN1USP2MAOA | |
| SCHEMBL2885969 | 0.76 | HTT (0.44) | HTTKMT2AMEN1USP2MAOA | |
| Potassium Ion SCHEMBL4430077 | 0.74 | HTT (0.54) | HTTKMT2AMEN1USP2ATM | |
| SCHEMBL8507081 | 0.74 | HTT (0.54) | HTTKMT2AMEN1USP2ATM | |
| SCHEMBL2230565 | 0.74 | HTT (0.54) | HTTKMT2AMEN1USP2ATM | |
| SCHEMBL8506452 | 0.74 | HTT (0.54) | HTTKMT2AMEN1USP2ATM | |
| SCHEMBL2124488 | 0.72 | HTT (0.40) | HTTKMT2AMEN1USP2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443483-A1 | MULTI-ARMED MACROMONOMERS, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING SAME | Bausch & Lomb Incorporated (US) | 2012-04-25 | — | — | EP | disclosed |