Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2124488 | 0.95 | HTT (0.40) | HTTKMT2AMEN1USP2MAOA | |
| SCHEMBL2125823 | 0.79 | HTT (0.46) | HTTKMT2AMEN1USP2MAOA | |
| SCHEMBL2736393 | 0.79 | MAOA (0.50) | KMT2AMEN1USP2MAOAL3MBTL1 | |
| SCHEMBL2124307 | 0.76 | HTT (0.46) | HTTKMT2AMEN1USP2MAOA | |
| SCHEMBL31545658 | 0.75 | LMNA (0.41) | KMT2AMEN1USP2MAOAGRM8 | |
| SCHEMBL2885668 | 0.75 | HTT (0.45) | HTTKMT2AMEN1USP2MAOA | |
| SCHEMBL28256758 | 0.75 | HTT (0.45) | HTTKMT2AMEN1USP2MAOA | |
| SCHEMBL3088498 | 0.74 | KMT2A (0.40) | HTTKMT2AMEN1USP2MAOA | |
| SCHEMBL79265 | 0.73 | MAOA (0.48) | HTTKMT2AMEN1USP2MAOA | |
| SCHEMBL3092190 | 0.73 | KMT2A (0.37) | HTTKMT2AMEN1USP2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100315588-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |