Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2124307 | 0.86 | HTT (0.46) | HTTCYP2C9KMT2AMEN1USP2 | |
| SCHEMBL2125823 | 0.86 | HTT (0.46) | HTTCYP2C9KMT2AMEN1USP2 | |
| SCHEMBL1423891 | 0.80 | HTT (0.48) | HTTCYP2C9KMT2AMEN1USP2 | |
| SCHEMBL5500670 | 0.78 | MEN1 (0.41) | HTTCYP2C9KMT2AMEN1USP2 | |
| SCHEMBL11781441 | 0.78 | CYP2C9 (0.44) | HTTCYP2C9KMT2AMEN1MAOA | |
| SCHEMBL11855411 | 0.76 | CYP2C9 (0.42) | HTTCYP2C9KMT2AMEN1MAOA | |
| SCHEMBL5475173 | 0.76 | CYP2C9 (0.46) | CYP2C9KMT2AMEN1MAOATSHR | |
| SCHEMBL9407337 | 0.76 | AHR (0.46) | HTTCYP2C9KMT2AMEN1MAOA | |
| SCHEMBL40368 | 0.76 | CYP2C9 (0.55) | HTTCYP2C9KMT2AMEN1USP2 | |
| SCHEMBL28256758 | 0.76 | HTT (0.45) | HTTKMT2AMEN1USP2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443483-B1 | MULTI-ARMED MACROMONOMERS, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING SAME. | BAUSCH & LOMB (US) | 2016-03-23 | — | — | EP | disclosed |
| US-9285508-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2016-03-15 | — | — | US | disclosed |
| WO-2010147865-A1 | MULTI-ARMED MACROMONOMERS, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING SAME | BAUSCH & LOMB INCORPORATED (US) | 2010-12-23 | — | — | WO | disclosed |
| US-20100318185-A1 | Biomedical Devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |