Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.82 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18086937 | 0.97 | ELANE (0.87) | ELANECYP2C19CYP2C9 | |
| SCHEMBL123537 | 0.97 | ELANE (0.87) | ELANECYP2C19CYP2C9 | |
| SCHEMBL122465 | 0.97 | ELANE (0.87) | ELANECYP2C19CYP2C9 | |
| SCHEMBL123843 | 0.90 | ELANE (1.00) | ELANECYP2C19CYP2C9 | |
| SCHEMBL125346 | 0.90 | ELANE (1.00) | ELANECYP2C19CYP2C9 | |
| SCHEMBL3719477 | 0.89 | ELANE (0.86) | ELANECYP2C19CYP2C9 | |
| SCHEMBL122597 | 0.89 | ELANE (0.86) | ELANECYP2C19CYP2C9 | |
| SCHEMBL123572 | 0.89 | ELANE (0.73) | ELANECYP2C19CYP2C9 | |
| SCHEMBL121885 | 0.88 | ELANE (0.72) | ELANECYP2C19CYP2C9 | |
| SCHEMBL121094 | 0.88 | ELANE (0.72) | ELANECYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10676443-B2 | Method for producing (4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile | PH PHARMA CO., LTD. (KR) | 2020-06-09 | — | — | US | disclosed |
| CN-110981815-A | Process for producing a compound | PH制药有限公司 | 2020-04-10 | — | — | CN | disclosed |
| US-20190248750-A1 | METHOD FOR PRODUCING (4S)-4-[4-CYANO-2-(METHYLSULFONYL)PHENYL]-3,6-DIMETHYL-2-OXO-1-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,3,4-TETRAHYDRO PYRIMIDINE-5-CARBONITRILE | PH PHARMA CO., LTD. (KR) | 2019-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190248750-A1 | METHOD FOR PRODUCING (4S)-4-[4-CYANO-2-(METHYLSULFONYL)PHENYL]-3,6-DIMETHYL-2-OXO-1-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,3,4-TETRAHYDRO PYRIMIDINE-5-CARBONITRILE | CYP2S1, PFAS, DPYD | ELANE 4588/4885CYP2C19 1086/4885CYP2C9 530/4885 |
| US-10676443-B2 | Method for producing (4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile | CYP2S1, PFAS, DPYD | ELANE 4588/4885CYP2C19 1086/4885CYP2C9 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.