SCHEMBL21243680

SCHEMBL21243680

C#CCC(C(=O)O)[C@H](C)N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 3/20 0.47
GRIK2 Q13002 3/20 0.47
SLC1A3 P43003 3/20 0.42
SLC1A2 P43004 3/20 0.42
SLC1A1 P43005 2/20 0.42
SLC7A5 Q01650 2/20 0.37
CYP2D6 P10635 1/20 0.33
NFKB1 P19838 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
ENPEP Q07075 2/20 0.32
GABRP O00591 2/20 0.32
GABRD O14764 2/20 0.32
GABRA1 P14867 2/20 0.32
GABRB1 P18505 2/20 0.32
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32
GABRA5 P31644 2/20 0.32
GABRA3 P34903 2/20 0.32
GABRA2 P47869 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21243670 1.00 GRIK1 (0.47) GRIK1GRIK2SLC1A3SLC1A2SLC1A1
SCHEMBL7554466 0.82 SLC1A3 (0.45) GRIK1GRIK2SLC1A3SLC1A2SLC1A1
SCHEMBL7424012 0.82 GRIK1 (0.41) GRIK1GRIK2SLC1A3SLC1A2SLC1A1
SCHEMBL17212018 0.81 GRIK1 (0.46) GRIK1GRIK2SLC1A3SLC1A2SLC1A1
SCHEMBL16587582 0.74 GRIK1 (0.47) GRIK1GRIK2SLC1A3SLC1A2SLC1A1
SCHEMBL8847323 0.74 GRIK1 (0.35) GRIK1GRIK2SLC1A3SLC1A2SLC1A1
SCHEMBL7989232 0.74 CHRM1 (0.40) GRIK1GRIK2SLC1A3SLC1A2SLC1A1
SCHEMBL7718052 0.74 CHRM1 (0.40) GRIK1GRIK2SLC1A3SLC1A2SLC1A1
SCHEMBL6805457 0.73 TSHR (0.41) GRIK1GRIK2SLC1A3SLC1A2SLC1A1
SCHEMBL9860882 0.72 GRIK1 (0.37) GRIK1GRIK2SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109983026-B Carrier for mixed mode affinity chromatography 富士胶片株式会社 2023-09-19 CN disclosed
US-11565240-B2 Mixed mode affinity chromatography carrier FUJIFILM CORPORATION (JP) 2023-01-31 US disclosed
EP-3553073-A1 MIXED MODE AFFINITY CHROMATOGRAPHY CARRIER FUJIFILM Corporation (JP) 2019-10-16 EP disclosed
US-20190247827-A1 MIXED MODE AFFINITY CHROMATOGRAPHY CARRIER FUJIFILM CORPORATION (JP) 2019-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190247827-A1 MIXED MODE AFFINITY CHROMATOGRAPHY CARRIER FCGR2A, FCGR3B, FCGR1A GRIK1 2599/4885GRIK2 2321/4885SLC1A3 114/4885
US-11565240-B2 Mixed mode affinity chromatography carrier FCGR2A, FCGR3B, FCGR1A GRIK1 2599/4885GRIK2 2321/4885SLC1A3 114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.