Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | UTRN | P46939 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21243753 | 1.00 | HDAC6 (0.31) | HDAC6UTRNCYP1A2AHRHDAC3 | |
| SCHEMBL21243731 | 0.89 | HDAC6 (0.34) | HDAC6UTRNCYP1A2AHRHDAC3 | |
| SCHEMBL21243733 | 0.89 | HDAC6 (0.34) | HDAC6UTRNCYP1A2AHRHDAC3 | |
| SCHEMBL21243750 | 0.86 | HDAC6 (0.35) | HDAC6UTRNCYP1A2AHRHDAC3 | |
| SCHEMBL21810435 | 0.81 | CYP1A2 (0.30) | HDAC6UTRNCYP1A2AHR | |
| SCHEMBL21525980 | 0.81 | CYP1A2 (0.30) | HDAC6UTRNCYP1A2AHR | |
| SCHEMBL21243736 | 0.80 | UTRN (0.37) | HDAC6UTRNCYP1A2AHR | |
| SCHEMBL21919003 | 0.80 | UTRN (0.31) | UTRN | |
| SCHEMBL18795103 | 0.79 | UTRN (0.45) | HDAC6UTRNCYP1A2AHR | |
| SCHEMBL18760366 | 0.76 | UTRN (0.31) | HDAC6UTRNCYP1A2AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3536688-B1 | QUINOLINE COMPOUND HAVING OXIME GROUP, N-OXIDE OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING SAME AND METHOD FOR USE THEREOF | NIHON NOHYAKU CO LTD (JP) | 2023-03-29 | — | — | EP | disclosed |
| US-10435411-B2 | Oxime group-containing quinoline compound, N-oxide thereof or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | NIHON NOHYAKU CO., LTD. (JP) | 2019-10-08 | — | — | US | disclosed |
| EP-3536688-A1 | QUINOLINE COMPOUND HAVING OXIME GROUP, N-OXIDE OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING SAME AND METHOD FOR USE THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2019-09-11 | — | — | EP | disclosed |
| US-20190248796-A1 | OXIME GROUP-CONTAINING QUINOLINE COMPOUND, N-OXIDE THEREOF OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2019-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10435411-B2 | Oxime group-containing quinoline compound, N-oxide thereof or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | NOS2, NOS1, CBR3 | HDAC6 1252/4885UTRN 4866/4885CYP1A2 10/4885 |
| US-20190248796-A1 | OXIME GROUP-CONTAINING QUINOLINE COMPOUND, N-OXIDE THEREOF OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE | NOS2, NOS1, CBR3 | HDAC6 1252/4885UTRN 4866/4885CYP1A2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.