SCHEMBL21243904

SCHEMBL21243904

Clc1nccc2c1sc1ccsc12

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AXL P30530 1/20 0.42
MKNK1 Q9BUB5 1/20 0.42
MKNK2 Q9HBH9 1/20 0.42
DYRK1A Q13627 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
APEX1 P27695 1/20 0.33
MAPK1 P28482 1/20 0.33
PMP22 Q01453 1/20 0.33
GPR35 Q9HC97 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656585 1.00 AXL (0.42) AXLMKNK1MKNK2DYRK1AADORA2A
SCHEMBL24188604 0.79 GPR35 (0.39) GPR35
SCHEMBL29377266 0.75 AXL (0.48) AXLMKNK1MKNK2DYRK1AADORA2A
SCHEMBL660369 0.75 AXL (0.48) AXLMKNK1MKNK2DYRK1AADORA2A
SCHEMBL19220745 0.74 GPR35 (0.41) GPR35
SCHEMBL24795600 0.73 PDPK1 (0.40) ADORA1MAPTGPR35
SCHEMBL442331 0.73 GPR3 (0.46) LMNACYP3A4MAPTAPEX1MAPK1
SCHEMBL30967228 0.73 GPR3 (0.46) LMNACYP3A4MAPTAPEX1MAPK1
SCHEMBL9976818 0.72 GPR35 (0.39) GPR35
SCHEMBL29792714 0.71 HTR2C (0.45) AXLMKNK1MKNK2DYRK1AADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034190-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-01-30 US disclosed
US-12122794-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-10-22 US disclosed
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11697662-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
US-11697662-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
US-11697662-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
US-20220041636-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-02-10 US disclosed
US-11180519-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-11-23 US disclosed
US-11180519-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-11-23 US disclosed
US-20190248818-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-15 US disclosed
US-20190248818-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190248818-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR AXL 1274/4885MKNK1 4006/4885MKNK2 3866/4885
US-11180519-B2 Organic electroluminescent materials and devices LIFR, C1R, LBR AXL 1274/4885MKNK1 4006/4885MKNK2 3866/4885
US-20250034190-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR AXL 1185/4885MKNK1 3945/4885MKNK2 3784/4885
US-20220041636-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR AXL 1401/4885MKNK1 3860/4885MKNK2 3650/4885
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR AXL 1183/4885MKNK1 3964/4885MKNK2 3804/4885
US-12122794-B2 Organic electroluminescent materials and devices LIFR, C1R, LBR AXL 1183/4885MKNK1 3964/4885MKNK2 3804/4885
US-11697662-B2 Organic electroluminescent materials and devices LIFR, C1R, LBR AXL 1401/4885MKNK1 3860/4885MKNK2 3650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.