Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438143 | 0.78 | HIF1A (0.55) | SMN1; SMN2HIF1ASLC6A2TAAR1CYP1A2 | |
| SCHEMBL2351133 | 0.77 | KDM4E (0.57) | SMN1; SMN2HIF1ASLC6A2TAAR1KDM4E | |
| SCHEMBL2008546 | 0.77 | CYP1A2 (0.46) | SMN1; SMN2HIF1ASLC6A2TAAR1KDM4E | |
| SCHEMBL465335 | 0.77 | KDM4E (0.57) | SMN1; SMN2HIF1ASLC6A2TAAR1KDM4E | |
| SCHEMBL5885752 | 0.77 | TAAR1 (0.58) | SMN1; SMN2HIF1ASLC6A2TAAR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3889042 | 0.76 | KDM4E (0.55) | SMN1; SMN2HIF1ASLC6A2TAAR1KDM4E | |
| SCHEMBL2212225 | 0.75 | KDM4E (0.50) | SMN1; SMN2HIF1ASLC6A2TAAR1KDM4E | |
| SCHEMBL2024077 | 0.74 | SLC6A2 (0.61) | SMN1; SMN2HIF1ASLC6A2TAAR1KDM4E | |
| SCHEMBL7957804 | 0.74 | SLC6A2 (0.61) | SMN1; SMN2HIF1ASLC6A2TAAR1KDM4E | |
| SCHEMBL9539267 | 0.74 | KDM4E (0.53) | SMN1; SMN2HIF1ASLC6A2TAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190248956-A1 | POLY(L-LYSINE ISOLPHTHALAMIDE) (PLP) POLYMERS WITH HYDROPHOBIC PENDANT CHAINS | IMPERIAL INNOVATIONS LIMITED (GB) | 2019-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190248956-A1 | POLY(L-LYSINE ISOLPHTHALAMIDE) (PLP) POLYMERS WITH HYDROPHOBIC PENDANT CHAINS | PLP2, LNPEP, PLPBP | SMN1; SMN2 1283/4885HIF1A 1910/4885SLC6A2 3440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.