Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.47 |
| ▸ | GRM8 | O00222 | 2/20 | 0.47 |
| ▸ | GRM6 | O15303 | 2/20 | 0.47 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25355764 | 0.85 | GRM8 (0.59) | GRIK1GRIK2GRM8GRM6GRM7 | |
| SCHEMBL25355757 | 0.85 | GRM8 (0.59) | GRIK1GRIK2GRM8GRM6GRM7 | |
| SCHEMBL8658482 | 0.78 | GRIK1 (0.46) | GRIK1GRIK2GRM8GRM6GRM7 | |
| SCHEMBL22322158 | 0.76 | ALDH1A1 (0.53) | ALDH1A1PRSS1TMPRSS15 | |
| SCHEMBL27756613 | 0.73 | CYP2D6 (0.48) | GRIK1GRIK2GRM8GRM6GRM7 | |
| SCHEMBL30015378 | 0.72 | DPP4 (0.38) | GRIK1GRIK2ALDH1A1BLMKMT2A | |
| SCHEMBL29192552 | 0.72 | GRIK1 (0.40) | GRIK1GRIK2GRM8GRM6GRM7 | |
| SCHEMBL1768346 | 0.71 | GRM8 (0.55) | GRIK1GRIK2GRM8GRM6GRM7 | |
| SCHEMBL1768348 | 0.71 | GRM8 (0.55) | GRIK1GRIK2GRM8GRM6GRM7 | |
| SCHEMBL26008337 | 0.71 | GABRP (0.41) | GRIK1GRIK2GRM8GRM6GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190249165-A1 | MODIFIED ENZYME AND USE THEREOF | KANEKA CORPORATION (JP) | 2019-08-15 | — | — | US | disclosed |