SCHEMBL21244262

SCHEMBL21244262

C=Cc1cccc2cc(C)ccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.57
TDP1 Q9NUW8 2/20 0.44
TP53 P04637 1/20 0.44
CYP2A6 P11509 5/20 0.43
ALDH1A1 P00352 3/20 0.40
LMNA P02545 3/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
SIRT2 Q8IXJ6 1/20 0.38
SIRT1 Q96EB6 1/20 0.38
SIRT3 Q9NTG7 1/20 0.38
SIRT5 Q9NXA8 1/20 0.38
ACHE P22303 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
MAOA P21397 1/20 0.36
NQO2 P16083 1/20 0.35
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21244243 0.85 CYP1A2 (0.57) CYP1A2TDP1TP53CYP2A6ALDH1A1
SCHEMBL22689365 0.81 CYP2A6 (0.44) CYP1A2TDP1TP53CYP2A6ALDH1A1
SCHEMBL29955696 0.81 CYP1A2 (0.57) CYP1A2TDP1CYP2A6ALDH1A1LMNA
SCHEMBL9437612 0.81 CYP1A2 (0.57) CYP1A2TDP1CYP2A6ALDH1A1LMNA
SCHEMBL12986970 0.78 TP53 (0.41) CYP1A2TDP1TP53ALDH1A1KDM4E
SCHEMBL29592963 0.78 TP53 (0.41) CYP1A2TDP1TP53ALDH1A1KDM4E
SCHEMBL21045089 0.78 CYP1A2 (0.55) CYP1A2TDP1TP53CYP2A6ALDH1A1
SCHEMBL1506789 0.77 CYP1A2 (0.43) CYP1A2LMNANQO2ESR2
SCHEMBL30365636 0.77 CYP1A2 (0.43) CYP1A2LMNANQO2ESR2
SCHEMBL27471959 0.77 CYP1A2 (0.43) CYP1A2CYP2A6ALDH1A1SIRT2SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190250509-A1 PHOTOSENSITIVE COMPOSITION AND ORGANIC THIN-FILM TRANSISTOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-08-15 US disclosed
US-20190250510-A1 PHOTOSENSITIVE COMPOSITION AND ORGANIC THIN-FILM TRANSISTOR SUMITOMO CHEMICAL COMPANY, LIMITED. (JP) 2019-08-15 US disclosed