SCHEMBL21244243

SCHEMBL21244243

C=Cc1cccc2ccc(C)cc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.57
CYP2A6 P11509 5/20 0.57
TDP1 Q9NUW8 3/20 0.44
TP53 P04637 1/20 0.44
MAOA P21397 1/20 0.42
ALDH1A1 P00352 5/20 0.36
ACHE P22303 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
NQO2 P16083 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KDM4E B2RXH2 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 1/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21244262 0.85 CYP1A2 (0.57) CYP1A2CYP2A6TDP1TP53MAOA
SCHEMBL22689365 0.81 CYP2A6 (0.44) CYP1A2CYP2A6TDP1TP53MAOA
SCHEMBL2138975 0.81 CYP2A6 (0.57) CYP1A2CYP2A6TDP1MAOAALDH1A1
SCHEMBL29955718 0.81 CYP2A6 (0.57) CYP1A2CYP2A6TDP1MAOAALDH1A1
SCHEMBL29760312 0.78 TYMS (0.42) CYP1A2CYP2A6TDP1TP53ALDH1A1
SCHEMBL2443320 0.78 TYMS (0.42) CYP1A2CYP2A6TDP1TP53ALDH1A1
SCHEMBL28305359 0.77 ALDH1A1 (0.61) CYP1A2CYP2A6TDP1MAOAALDH1A1
SCHEMBL1506773 0.77 MCL1 (0.49) CYP1A2NQO2KDM4ELMNAMEN1
SCHEMBL4516955 0.77 CYP1A2 (0.48) CYP1A2CYP2A6TDP1TP53ALDH1A1
SCHEMBL31656345 0.77 MTNR1A (0.56) CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190250509-A1 PHOTOSENSITIVE COMPOSITION AND ORGANIC THIN-FILM TRANSISTOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-08-15 US disclosed
US-20190250510-A1 PHOTOSENSITIVE COMPOSITION AND ORGANIC THIN-FILM TRANSISTOR SUMITOMO CHEMICAL COMPANY, LIMITED. (JP) 2019-08-15 US disclosed