SCHEMBL2124452

SCHEMBL2124452

CCC(=O)c1cccc2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.67
ALDH1A1 P00352 5/20 0.62
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
MAPT P10636 4/20 0.62
HPGD P15428 3/20 0.62
KDM4E B2RXH2 3/20 0.62
GMNN O75496 2/20 0.62
LMNA P02545 2/20 0.62
POLB P06746 2/20 0.62
MAPK1 P28482 2/20 0.62
BLM P54132 2/20 0.62
PMP22 Q01453 2/20 0.62
NPSR1 Q6W5P4 2/20 0.62
CMKLR1 Q99788 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
TP53 P04637 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2D6 P10635 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29473553 1.00 PTPN1 (0.67) PTPN1ALDH1A1MEN1KMT2AMAPT
Hydrochloric Acid SCHEMBL27702616 0.98 PTPN1 (0.65) PTPN1ALDH1A1MEN1KMT2AMAPT
Dimethylamine SCHEMBL6806578 0.94 PTPN1 (0.61) PTPN1ALDH1A1MEN1KMT2AMAPT
Methoxymethane SCHEMBL29175314 0.94 PTPN1 (0.61) PTPN1ALDH1A1MEN1KMT2AMAPT
SCHEMBL28879996 0.89 PTPN1 (0.54) PTPN1ALDH1A1MEN1KMT2AMAPT
SCHEMBL29875165 0.89 PTPN1 (0.54) PTPN1ALDH1A1MEN1KMT2AMAPT
SCHEMBL27658813 0.88 NR4A1 (0.61) PTPN1ALDH1A1MEN1KMT2AMAPT
SCHEMBL1716864 0.86 ALDH1A1 (0.70) PTPN1ALDH1A1MEN1KMT2AMAPT
SCHEMBL29875679 0.86 ALDH1A1 (0.70) PTPN1ALDH1A1MEN1KMT2AMAPT
SCHEMBL5857951 0.83 PTPN1 (0.71) PTPN1ALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108570696-B High-current-density-resistant acidic zinc-nickel electroplating solution and application thereof 广东达志化学科技有限公司 2020-06-02 CN claimed
CN-108570696-A A kind of acidic zinc nickel plating solution of resistance to high current density and its application 广州市海科顺表面处理有限公司 2018-09-25 CN claimed
CN-106894064-A A kind of special acid electroplated zinc nickel alloy electrolyte of transformer case casting 南通市海王电气有限公司 2017-06-27 CN claimed
EP-3122320-A1 SKIN ENGAGING SHAVNG AID COMPRISING A THERMALLY RESILIENT SENSATE AND A TRPA1 RECEPTOR INHIBITOR The Gillette Company LLC (US) 2017-02-01 EP claimed
US-20160155958-A1 BICYCLIC IRIDIUM COMPLEX AND PROCESS FOR PREPARING SAME, ORGANIC LIGHT EMITTING DEVICE AND PROCESS FOR PREPARING SAME HEFEI BOE OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2016-06-02 US claimed
WO-2015148308-A1 SKIN ENGAGING SHAVNG AID COMPRISING A THERMALLY RESILIENT SENSATE AND A TRPA1 RECEPTOR INHIBITOR THE GILLETTE COMPANY (US) 2015-10-01 WO claimed
CN-104694983-A Acidic electroplating zinc-nickel alloy electrolyte, preparation method and electroplating method NANJING CHUANGYUAN CHEMICAL TECHNOLOGY CO LTD 2015-06-10 CN claimed
CN-101180302-B Process for preparing (alpha s, beta r)-6-bromo-alpha-[2-(dimethylamino)ethyl]-2-methoxy-alpha-1-naphthalenyl-beta-phenyl-3-quinolineethanol JANSSEN PHARMACEUTICA NV 2013-06-19 CN claimed
US-8378216-B2 Energy cable PRYSMIAN S.P.A. (IT) 2013-02-19 US claimed
CN-101548340-B Energy cable PRYSMIAN CO LTD 2013-01-30 CN claimed
US-20100126756-A1 ENERGY CABLE PRYSMIAN CAVIESISTEMI ENERGIA (IT) 2010-05-27 US claimed
CN-101585819-A Preparation method for 1,2,3-thiadiazole thioacetanilides derivatives UNIV SHANDONG (CN) 2009-11-25 CN claimed
CN-101548340-A Energy cable PRYSMIAN CO LTD 2009-09-30 CN claimed
EP-2092535-A1 ENERGY CABLE Prysmian S.p.A. (IT) 2009-08-26 EP claimed
WO-2008058572-A1 ENERGY CABLE PRYSMIAN S.P.A. (IT) 2008-05-22 WO claimed
CN-101180302-A Process for preparing (alpha s, beta r)-6-bromo-alpha-[2-(dimethylamino)ethyl]-2-methoxy-alpha-1-naphthalenyl-beta-phenyl-3-quinolineethanol JANSSEN PHARMACEUTICA NV (BE) 2008-05-14 CN claimed
WO-2004065411-A2 PEPTIDES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2004-08-05 WO claimed
EP-0284297-B1 HALOGENATED NAPHTHALENE DERIVATIVES NIPPON OIL CO. LTD. (JP) 1990-12-27 EP claimed
US-4803013-A IMPROVED DIELECTRIC PROPERTIES, HYDROGEN ABSORPTION, FLUIDITY, VISCOSITY STABILITY NIPPON OIL CO., LTD. (JP) 1989-02-07 US claimed
EP-0284297-A1 Halogenated Naphthalene Derivatives NIPPON OIL CO. LTD. (JP) 1988-09-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160155958-A1 BICYCLIC IRIDIUM COMPLEX AND PROCESS FOR PREPARING SAME, ORGANIC LIGHT EMITTING DEVICE AND PROCESS FOR PREPARING SAME ORC3, INO80C, INTS9 PTPN1 4610/4885ALDH1A1 875/4885MEN1 2655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.