Dimethylamine

Dimethylamine

SCHEMBL6806578

CCC(=O)c1cccc2ccccc12.CNC

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.61
PLK1 P53350 1/20 0.61
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
ALDH1A1 P00352 5/20 0.57
MAPT P10636 3/20 0.57
HPGD P15428 3/20 0.57
KDM4E B2RXH2 3/20 0.57
LMNA P02545 3/20 0.57
POLB P06746 3/20 0.57
GMNN O75496 2/20 0.57
MAPK1 P28482 2/20 0.57
BLM P54132 2/20 0.57
PMP22 Q01453 2/20 0.57
NPSR1 Q6W5P4 2/20 0.57
CMKLR1 Q99788 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
TP53 P04637 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP3A4 P08684 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2124452 0.94 PTPN1 (0.67) PTPN1PLK1MEN1KMT2AALDH1A1
SCHEMBL29473553 0.94 PTPN1 (0.67) PTPN1PLK1MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL27702616 0.93 PTPN1 (0.65) PTPN1PLK1MEN1KMT2AALDH1A1
Methoxymethane SCHEMBL29175314 0.89 PTPN1 (0.61) PTPN1PLK1MEN1KMT2AALDH1A1
SCHEMBL28879996 0.84 PTPN1 (0.54) PTPN1PLK1MEN1KMT2AALDH1A1
SCHEMBL29875165 0.84 PTPN1 (0.54) PTPN1PLK1MEN1KMT2AALDH1A1
SCHEMBL27658813 0.83 NR4A1 (0.61) PTPN1PLK1MEN1KMT2AALDH1A1
SCHEMBL5857951 0.83 PTPN1 (0.71) PTPN1PLK1MEN1KMT2AALDH1A1
SCHEMBL29457006 0.83 PTPN1 (0.71) PTPN1PLK1MEN1KMT2AALDH1A1
SCHEMBL1716864 0.81 ALDH1A1 (0.70) PTPN1PLK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117399070-A Chiral metal synergistic catalytic system containing chelating ligand and application of chiral metal synergistic catalytic system in asymmetric synthesis of bedaquiline 上海交通大学 2024-01-16 CN claimed
US-5717217-A Method for determining thickness, degree of cure and other properties of a polymeric coating SPECTRA GROUP LIMITED, INC. (US) 1998-02-10 US claimed
US-5606171-A USING A FLUORESCENT DETECTOR SPECTRA GROUP LIMITED, INC. (US) 1997-02-25 US claimed
CN-117399070-A Chiral metal synergistic catalytic system containing chelating ligand and application of chiral metal synergistic catalytic system in asymmetric synthesis of bedaquiline 上海交通大学 2024-01-16 CN disclosed
WO-2024007621-A1 BI-CHIRAL METALLIC SYNERGIC CATALYSIS SYSTEM COMPRISING CHELATING LIGAND AND USE THEREOF IN ASYMMETRIC SYNTHESIS OF BEDAQUILINE 上海交通大学 2024-01-11 WO disclosed
CN-116603570-A Double-chiral metal synergistic catalytic system and application thereof in asymmetric synthesis of bedaquiline 上海交通大学 2023-08-18 CN disclosed
WO-2023151700-A1 DOUBLE-CHIRAL METAL COOPERATIVE CATALYSIS SYSTEM AND USE THEREOF IN ASYMMETRIC SYNTHESIS OF BEDAQUILINE 上海交通大学 2023-08-17 WO disclosed
US-6764710-B2 Light emitting markers for use with substrates SCIMED LIFE SYSTEMS, INC. 2004-07-20 US disclosed
WO-2003008009-A1 LIGHT EMITTING MARKERS FOR USE WITH SUBSTRATES SCIMED LIFE SYSTEMS, INC. (US) 2003-01-30 WO disclosed
US-20030015284-A1 SATURATING WITH MIXTURE OF COPOLYMERS OF DIMETHYLSILOXANE AND POLYSTYRENE; DRAINAGE, DRYING, COATING, REMOVAL AND POLISHING; FLOWER SHAPE, TEXTURE, SIZE, AND COLOR IS RETAINED; WEAR RESISTANCE, DURABILITY BOSTON SCIENTIFIC SCIMED, INC. 2003-01-23 US disclosed
US-6461326-B1 Fluorescent dyed adhesive for bonding various components in a medical device SCIMED LIFE SYSTEMS, INC. 2002-10-08 US disclosed