Bicarbonate

Bicarbonate

SCHEMBL2124476

CCCCC1(OO)CCCCC1.O=C(O)O.O=C(O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TSHR P16473 1/20 0.36
CETP P11597 4/20 0.35
CTSL P07711 2/20 0.34
CTSB P07858 2/20 0.34
CTSK P43235 2/20 0.34
SLC6A5 Q9Y345 1/20 0.33
NAAA Q02083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL5672941 1.00 MEN1 (0.40) MEN1KMT2ATSHRCETPCTSL
SCHEMBL28146746 0.92 MEN1 (0.33) MEN1KMT2ATSHRCETPSLC6A5
SCHEMBL28667413 0.86 CETP (0.33) MEN1KMT2ACETPSLC6A5NAAA
Bicarbonate SCHEMBL11258154 0.82 TSHR (0.38) MEN1KMT2ATSHRCTSLCTSB
SCHEMBL27864167 0.82
SCHEMBL11640879 0.81 MEN1 (0.40) MEN1KMT2ATSHRCETPCTSL
SCHEMBL27480154 0.80 TSHR (0.32) TSHR
SCHEMBL11640875 0.79 MEN1 (0.37) MEN1KMT2ACETPCTSLCTSB
SCHEMBL11042160 0.79 MEN1 (0.35) MEN1KMT2ACETPCTSLCTSB
SCHEMBL11565652 0.79 CES2 (0.38) MEN1KMT2ACETPCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10766814-B2 Artificial marble composition and production method for artificial marble using same LG HAUSYS, LTD. (KR) 2020-09-08 US claimed
EP-3385240-B1 METHOD FOR MANUFACTURING ARTIFICIAL MARBLE LG HAUSYS LTD (KR) 2020-04-29 EP claimed
EP-3385240-A1 ARTIFICIAL MARBLE COMPOSITION AND PRODUCTION METHOD FOR ARTIFICIAL MARBLE USING SAME LG Hausys, Ltd. (KR) 2018-10-10 EP claimed
US-20180282215-A1 ARTIFICIAL MARBLE COMPOSITION AND PRODUCTION METHOD FOR ARTIFICIAL MARBLE USING SAME LG HAUSYS, LTD. (KR) 2018-10-04 US claimed
WO-2022055307-A1 PRECURSOR COMPOSITION FOR POLYMER ELECTROLYTE, AND GEL POLYMER ELECTROLYTE FORMED THEREFROM 주식회사 엘지에너지솔루션 2022-03-17 WO disclosed
US-10766814-B2 Artificial marble composition and production method for artificial marble using same LG HAUSYS, LTD. (KR) 2020-09-08 US disclosed
EP-3385240-B1 METHOD FOR MANUFACTURING ARTIFICIAL MARBLE LG HAUSYS LTD (KR) 2020-04-29 EP disclosed
EP-3385240-A1 ARTIFICIAL MARBLE COMPOSITION AND PRODUCTION METHOD FOR ARTIFICIAL MARBLE USING SAME LG Hausys, Ltd. (KR) 2018-10-10 EP disclosed
US-20180282215-A1 ARTIFICIAL MARBLE COMPOSITION AND PRODUCTION METHOD FOR ARTIFICIAL MARBLE USING SAME LG HAUSYS, LTD. (KR) 2018-10-04 US disclosed
EP-2443162-A1 COPOLYCONDENSATION POLYMERIZATION OF FLUOROPOLYMERS DuPont Performance Elastomers L.L.C. (US) 2012-04-25 EP disclosed
WO-2010147696-A1 COPOLYCONDENSATION POLYMERIZATION OF FLUOROPOLYMERS DUPONT PERFORMANCE ELASTOMERS L.L.C. (US) 2010-12-23 WO disclosed
WO-2008028918-A1 PROCESS FOR PREPARING A VINYLIDENE CHLORIDE POLYMER COMPOSITION AND FILMS AND PACKAGINGS OBTAINED FROM SAID COMPOSITION SOLVAY (SOCIETE ANONYME) (BE) 2008-03-13 WO disclosed
WO-1997045482-A1 PREPARATION OF ALKYLTHIOPROPIONIC PENTAERYTHRITOL ESTERS HAMPSHIRE CHEMICAL CORP. (US) 1997-12-04 WO disclosed
EP-0346996-A2 Process for preparing organic glasses GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) 1989-12-20 EP disclosed
EP-0146138-B1 MELT MOLDING MATERIAL KURARAY CO., LTD. (JP) 1988-12-28 EP disclosed
EP-0052166-B1 PROCESS FOR THE PREPARATION OF POLYMER BONDED CONCRETES PLASTIBETON CANADA INC (CA) 1986-02-26 EP disclosed
US-4547481-A DISPERSION CONTAINING FREE-RADICAL FORMING INITIATOR AND ETHOXYLATED NONIONIC EMULSIFIERS KENOGARD AB (SE) 1985-10-15 US disclosed
US-4499250-A ADDING THE FREE RADICAL INITIATOR IN AN AQUEOUS DISPERSION CONTAINING AN ETHOXYLATED NONIONIC EMULSIFIER; POLYVINYL CHLORIDE KENOGARD AB (SE) 1985-02-12 US disclosed
US-4415716-A AQUEOUS DISPERSIONS OF FREE RADICAL CATALYSTS USING BLEND OF NONIONIC EMULSIFIERS; STORAGE STABILITY; DIELECTRICS KENOGARD AB (SE) 1983-11-15 US disclosed
US-4209600-A ARYLSULFONIC ACID SOLVAY & CIE. (BE) 1980-06-24 US disclosed